ProfessorJim Coxon

My research interest is in understanding organic reactions, particularly those of value in synthesis and or biochemistry. Many of our studies have involved the timing of molecular events and the difference in energy of competing processes including: strained small ring opening and molecular rearrangement, factors responsible for facial selection in cycloaddition reactions and - reactions at carbonyls, and the use of chiral templates in inducing selection. Other interests include molecular modelling studies (ab initio studies of strained ring rearrangements, carbohydrate solution properties, macrocyclic conformational problems and protein structure) and Cataract research (a joint project with Professor Andrew Abell and colleagues at Lincoln focuses in development of calpain inhibitors).