Associate ProfessorSteven Gieseg

Aggregation of LDL

OxLDL induced cell death

Lipoxygenase inhibition

Down regulation of 7,8-Dihydroneopterin synthesis

OxLDL mediated cell death in U937 cells

Statin inhibition of PBMC and Plaque interferon activated inflammation

7,8-Dihydroneopterin inhibition of lipoxygenase

Developing SPCCT and Inflammatory Biomarker Analysis for Combined Medical Investigation

Oxidative stress from oxLDL

Application of nanoparticle contrast agents for spectral imaging of artery plaques

Development of inflammatory diagnostic technique using urinary neopterin

Effect of Statins of pterin synthesis

Macrophage Cell death

Identification and quantification of atherosclerotic plaque using MARS spectral photon-counting CT, and its transition to patient imaging

Role of TLR in NOX activation

7,8-dihydroneopterin down regulation of inflammation

Identification of the Kinase Cascades Mediating Oxidised Low Density Lipoprotein-Induced Intracellular Oxidative Stress

Mechanism of oxLDL causing chop activation during ER-stress and its inhibition by macrophage antioxidant 7,8-Dihydroneopterin in u937 cells

Induction of the Innate Immune Response by Physical Trauma and Infection: Quantification Through Analysis of Biochemical Markers

Regulation of the CD36 scavenger receptor by the antioxidant 7,8-dihydroneopterin

7,8-dihydroneopterin oxidation: Identifying the source of cellular neopterin generation during inflammation

Atherosclerotic plaque biochemistry and MARS spectral imaging

Identification of OxLDL-Induced oxidative stress sources in cardiovascular disease

Mechanism of 7,8-dihydroneopterin to downregulate CD36 scavenger receptor and foam cell formation

7,8-Dihydroneopterin oxidation