EquipmentLow Volume Isothermal Titration Calorimeter (ITC)

Ernest Rutherford Instrument Room 511
University of Canterbury
SPCS
20 Kirkwood Ave, Upper Riccarton
Christchurch
Canterbury
8041
New Zealand

Description

ITC is widely used in drug discovery, target validation, and structure activity relationship studies. ITC measures the absorption or generation of heat when a known volume of ligand is injected into a protein solution. The integrated areas under each injection peak are plotted against the molar ratio of the active species to directly determine enthalpy change (ΔH), binding constant (Ka) and stoichiometry (n). Low volume 190µl.

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Contacts

DEPARTMENT

  • School of Physical and Chemical Sciences

BUILDING

  • Ernest Rutherford

AVAILABILITY

  • Available for internal use only

Location

Ernest Rutherford Instrument Room 511
University of Canterbury
SPCS
20 Kirkwood Ave, Upper Riccarton
Christchurch
Canterbury
8041
New Zealand