EquipmentAKTA Pure

My research is primarily interested in how proteins do their jobs, and the myriad of structural forms and interactions that affect their functioning. By using structure-function relationships as a scaffold, I am interested in how this function can be tuned to yield desirable functional features. This research involves studying both soluble and membrane proteins, with an emphasis on studying enzymes. Alongside the proteinaceous research, I am interested in fundamental aspects of mass spectrometry analyses of proteins, and developing supporting software, to uncover new and enabling methodologies.

The research combines structural biology, mass spectrometry, biochemistry, and synthetic biology to investigate the molecular mechanisms of proteins and enzymes, with applications ranging from bioplastic production to antimicrobial resistance and drug discovery.