EquipmentBruker Avance III HD 600MHz Single Bay NMR Spectrometer with Triple-resonance Probe and Cooled SampleJet

The Bruker Avance III HD 600 MHz Nuclear Magnetic Resonance (NMR) Spectrometer is a state-of-the-art instrument designed for high-resolution structural and dynamic studies across chemistry, biology, and materials science. For research partners, the Avance III HD 600 MHz offers a powerful analytical platform capable of producing detailed molecular insights with outstanding efficiency, reproducibility, and throughput and is currently the only equipment of its type in Aotearoa New Zealand. Equipped with high-definition RF electronics and a 600 MHz (14.1 T) superconducting magnet, it delivers exceptional spectral sensitivity and stability for both proton and heteronuclear experiments. The triple-resonance cryoprobe (^1H/^13C/^15N) enables advanced multidimensional NMR applications, including detailed analysis of proteins, nucleic acids, and complex biomolecular interactions, while the cooled probe design significantly enhances signal-to-noise ratios for low-concentration or low-sensitivity nuclei. The integrated cooled SampleJet system automates sample handling, supporting high-throughput workflows and precise temperature control, making it ideal for both large-scale screening and time-sensitive studies. With variable-temperature operation, Z-gradient capabilities, and broad multinuclear detection—from ^19F and ^31P to other X-nuclei—the system provides unmatched versatility for applications ranging from structural biology and metabolomics to small-molecule characterisation and reaction monitoring. This instrument also allows for the analysis of large biological molecules such as proteins, nucleic acids and carbohydrates.

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